Deducing the symmetry of helical assemblies: Applications to membrane proteins
نویسندگان
چکیده
منابع مشابه
A unified convention for biological assemblies with helical symmetry
Assemblies with helical symmetry can be conveniently formulated in many distinct ways. Here, a new convention is presented which unifies the two most commonly used helical systems for generating helical assemblies from asymmetric units determined by X-ray fibre diffraction and EM imaging. A helical assembly is viewed as being composed of identical repetitive units in a one- or two-dimensional l...
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Helix packing is important in the folding, stability, and association of membrane proteins. Packing analysis of the helical portions of 7 integral membrane proteins and 37 soluble proteins show that the helices in membrane proteins have higher packing values (0.431) than in soluble proteins (0.405). The highest packing values in integral membrane proteins originate from small hydrophobic (G and...
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The development of techniques for making helical and semiconductor metallic nanoand microstructures represents the extension of the works of Da Vinci and Archimedes with modern scientifi c tools. It brings forth interesting application concepts along with tough challenges in optics, biology, and mechanics. Making helical metallic objects with submicrometer pitch lengths comparable to the wavele...
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MOTIVATION Prediction methods are of great importance for membrane proteins as experimental information is harder to obtain than for globular proteins. As more membrane protein structures are solved it is clear that topology information only provides a simplified picture of a membrane protein. Here, we describe a novel challenge for the prediction of alpha-helical membrane proteins: to predict ...
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The prediction of transmembrane helical segments (TMHs) in membrane proteins is an important field in the bioinformatics research. In this paper, a method based on discrete wavelet transform (DWT) has been developed to predict the number and location of TMHs in membrane proteins. PDB coded as 1F88 was chosen as an example to describe the prediction of the number and location of TMHs in membrane...
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ژورنال
عنوان ژورنال: Journal of Structural Biology
سال: 2016
ISSN: 1047-8477
DOI: 10.1016/j.jsb.2016.05.011